Clot stability as a determinant of effective factor VIII replacement in hemophilia A

Volume: 1, Issue: 2, Pages: 231 - 241
Published: Aug 10, 2017
Abstract
Factor VIII (FVIII) replacement is standard of care for patients with hemophilia A (HemA); however, patient response does not always correlate with FVIII levels. We hypothesize this may be in part due to the physical properties of clots and contributions of fibrin, platelets, and erythrocytes, which may be important for hemostasis.To understand how FVIII contributes to effective hemostasis in terms of clot structure and mechanical properties.In...
Paper Details
Title
Clot stability as a determinant of effective factor VIII replacement in hemophilia A
Published Date
Aug 10, 2017
Volume
1
Issue
2
Pages
231 - 241
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