Depression—A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer

ContextQuality of life (QoL) and depression are important patient-reported outcomes in cancer care. However, the relative importance of depression severity in predicting QoL remains unclear because of few methodologically sound studies.ObjectivesTo examine whether depression contributes to impairment of QoL irrespective of prognostic factors and symptom burden.MethodsA total of 563 patients were included from the European Palliative Care...