Review paper
HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology
Abstract
Plasma levels of HDL cholesterol (HDL-C) predict the risk of cardiovascular disease at the epidemiological level, but a direct causal role for HDL in cardiovascular disease remains controversial. Studies in animal models and humans with rare monogenic disorders link only particular HDL-associated mechanisms with causality, including those mechanisms related to particle functionality rather than cholesterol content. Mendelian randomization...
Paper Details
Title
HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology
Published Date
Aug 10, 2017
Journal
Volume
15
Issue
1
Pages
9 - 19
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