APOE genotype and early β-amyloid accumulation in older adults without dementia
Abstract
Objective:
To clarify associations between APOE ε4 allele and age on longitudinal rates of β-amyloid (Aβ) accumulation within Aβ+ and Aβ− older individuals without dementia.Methods:
We analyzed 595 older adults without dementia classified cross-sectionally as Aβ− (n = 325) and Aβ+ (n = 270) using longitudinal florbetapir PET. The influence of age and APOE genotype on longitudinal accumulation of Aβ was examined...Paper Details
Title
APOE genotype and early β-amyloid accumulation in older adults without dementia
Published Date
Sep 5, 2017
Journal
Volume
89
Issue
10
Pages
1028 - 1034
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