Sex-specific effects ofCOMTVal158Met polymorphism on corpus callosum structure: A whole-brain diffusion-weighted imaging study

Background Genetic polymorphisms play a significant role in determining brain morphology, including white matter structure and may thus influence the development of brain functions. The main objective of this study was to examine the effect of Val158Met (rs4680) polymorphism of Catechol-O-Methyltransferase (COMT) gene on white matter connectivity in healthy adults. Methods We used a whole-brain diffusion-weighted imaging method with Tract-Based...