Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism
Abstract
Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potential adverse effects in some individuals. The most common events associated with statin intolerance are myopathy and increased risk of developing type 2 diabetes mellitus. However, the pathological mechanism through...
Paper Details
Title
Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism
Published Date
Aug 9, 2017
Journal
Volume
5
Issue
1
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