The cubicon method for concentrating membrane proteins in the cubic mesophase
Abstract
The lipid cubic phase (in meso) method is an important approach for generating crystals and high-resolution X-ray structures of integral membrane proteins. However, as a consequence of instability, it can be impossible-using traditional methods-to concentrate certain membrane proteins and complexes to values suitable for in meso crystallization and structure determination. The cubicon method described here exploits the amphiphilic nature of...
Paper Details
Title
The cubicon method for concentrating membrane proteins in the cubic mesophase
Published Date
Aug 3, 2017
Journal
Volume
12
Issue
9
Pages
1745 - 1762
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