Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
Abstract
Taking the PERVs out of pigs With the severe shortage of organs needed for transplants, xenotransplantation (transplantation of nonhuman organs to humans) offers an alternative source. Some pig organs have similar size and function to those of humans. The challenge is that the pig genome harbors porcine endogenous retroviruses (PERVs) that can potentially pass to humans with possibly damaging consequences. Niu et al. generated pigs in which all...
Paper Details
Title
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
Published Date
Sep 22, 2017
Journal
Volume
357
Issue
6357
Pages
1303 - 1307
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