Histone Methyltransferase G9a Is Required for Cardiomyocyte Homeostasis and Hypertrophy
Abstract
Correct gene expression programming of the cardiomyocyte underlies the normal functioning of the heart. Alterations to this can lead to the loss of cardiac homeostasis, triggering heart dysfunction. Although the role of some histone methyltransferases in establishing the transcriptional program of postnatal cardiomyocytes during heart development has been shown, the function of this class of epigenetic enzymes is largely unexplored in the adult...
Paper Details
Title
Histone Methyltransferase G9a Is Required for Cardiomyocyte Homeostasis and Hypertrophy
Published Date
Sep 26, 2017
Journal
Volume
136
Issue
13
Pages
1233 - 1246
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