Construction of multifunctional porous silica nanocarriers for pH/enzyme-responsive drug release
Abstract
pH/enzyme-responsive nanocarriers based on porous silica (pSiO2) nanospheres (NSs) were developed for controlled release of drug. The pSiO2 NSs present uniform spheres and have an average diameter of 100nm. The pSiO2 NSs with high specific surface area (835m2·g-1) and the pore volume (1.24cm3·g-1) are suitable for drug loading and the loading capacity reaches to 29% for amoxicillin (AMX) model drug. In this system, protocatechuic acid (PCA) and...
Paper Details
Title
Construction of multifunctional porous silica nanocarriers for pH/enzyme-responsive drug release
Published Date
Dec 1, 2017
Volume
81
Pages
485 - 491
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