Development of postcompressional textural tests to evaluate the mechanical properties of medicated chewing gum tablets with high drug loadings
Abstract
Medicated chewing gum tablets (CGTs) represent a unique platform for drug delivery. Loading directly compressible gums with high concentrations of powdered medication, however, results in compacts with hybrid properties between a chewable gum and a brittle tablet. The aim of the present study was to develop textural tests that can identify the point at which CGTs begin to behave like a solid tablet upon drug incorporation. Curcumin (CUR) CGTs...
Paper Details
Title
Development of postcompressional textural tests to evaluate the mechanical properties of medicated chewing gum tablets with high drug loadings
Published Date
Aug 15, 2017
Journal
Volume
49
Issue
1
Pages
30 - 37
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