Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Abstract
Chemo-resistance, which is the main obstacle in cancer therapy, is caused by the onset of drug-resistant cells in the heterogeneous cell population in cancer tissues. MicroRNAs regulate gene expression at the post-transcriptional level, and they are involved in many different biological processes, including cell proliferation, differentiation, metabolism, stress response, and apoptosis. The aberrant expression of microRNAs plays a major...
Paper Details
Title
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Published Date
Jan 1, 2017
Journal
Volume
7
Issue
6
Pages
1350 - 1371
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