Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells
Abstract
Several studies have documented the ability of flavonoids to sensitize cancer cells to chemotherapeutics and reverse multidrug resistance by inhibition of efflux pumps (adenosine triphosphate-binding cassette transporters), apoptosis activation, and cell cycle arrest. In this study, the flavonoid rutin (quercetin 3-O-β-d-rutinoside) was investigated as chemosensitizer towards two different human epithelial breast cancer cell lines: (i)...
Paper Details
Title
Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells
Published Date
Jul 28, 2017
Journal
Volume
31
Issue
10
Pages
1529 - 1538
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