Abstract 5317: Association of physical activity with risk of prostate cancer defined byTMPRSS2:ERG

Background There is growing evidence of heterogeneity in risk factor associations for prostate cancer defined by clinical and molecular characteristics. Physical activity has moderate protective effects on development of prostate cancer, in particular of advanced and fatal disease. We hypothesized that the influence of physical activity on hormonal and anti-inflammatory pathways may differentially affect the development of TMPRSS2:ERG-positive...