A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis
Abstract
DNA double-strand breaks (DSBs) are a hazardous form of damage that can potentially cause cell death or genomic rearrangements. In mammalian G1- and G2-phase cells, DSBs are repaired with two-component kinetics. In both phases, a fast process uses canonical nonhomologous end joining (c-NHEJ) to repair the majority of DSBs. In G2, slow repair occurs by homologous recombination. The slow repair process in G1 also involves c-NHEJ proteins but...
Paper Details
Title
A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis
Published Date
Sep 1, 2017
Volume
42
Issue
9
Pages
690 - 701
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