Primary liver cancer genome sequencing: translational implications and challenges.
Abstract
The prognosis of primary liver cancer (PLC) remains poor and is explained by the slow progress in understanding the molecular pathways driving tumorigenesis, therapeutic resistance and relapse. For early PLCs, complete surgical resection is the only effective treatment, with sorafenib and, more recently, regorafenib prolonging overall survival by a few months. Areas covered: Application of next-generation sequencing (NGS), including targeted NGS...
Paper Details
Title
Primary liver cancer genome sequencing: translational implications and challenges.
Published Date
Oct 1, 2017
Journal
Volume
11
Issue
10
Pages
875 - 883
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Notes
History