Clinical study of genomic drivers in pancreatic ductal adenocarcinoma

Volume: 117, Issue: 4, Pages: 572 - 582
Published: Jul 18, 2017
Abstract
Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer with complex genomes and dense fibrotic stroma. This study was designed to identify clinically relevant somatic aberrations in pancreatic cancer genomes of patients with primary and metastatic disease enrolled and treated in two clinical trials. Tumour nuclei were flow sorted prior to whole genome copy number variant (CNV) analysis. Targeted or whole exome sequencing was performed on most...
Paper Details
Title
Clinical study of genomic drivers in pancreatic ductal adenocarcinoma
Published Date
Jul 18, 2017
Volume
117
Issue
4
Pages
572 - 582
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