Design and development of a biocompatible montmorillonite PLGA nanocomposites to evaluate in vitro oral delivery of insulin
Abstract
We are introducing design, development and preliminary feasibility study of nanocomposites (made of Food and drug administration approved layered montmorillonite (Mt) and biodegradable polymer Poly lactic-co-glycolic acid (PLGA)), as a vehicle for oral administration of insulin. A systematic study on the variation of Mt-PLGA ratio was focused to reduce particles to the submicron size range while maintaining insulin's bioactivity. The synthesized...
Paper Details
Title
Design and development of a biocompatible montmorillonite PLGA nanocomposites to evaluate in vitro oral delivery of insulin
Published Date
Oct 1, 2017
Journal
Volume
147
Pages
69 - 79
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