Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?
Volume: 74, Issue: 24, Pages: 4471 - 4509
Published: Jul 13, 2017
Abstract
Senescence is a cell state occurring in vitro and in vivo after successive replication cycles and/or upon exposition to various stressors. It is characterized by a strong cell cycle arrest associated with several molecular, metabolic and morphologic changes. The accumulation of senescent cells in tissues and organs with time plays a role in organismal aging and in several age-associated disorders and pathologies. Moreover, several therapeutic...
Paper Details
Title
Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?
Published Date
Jul 13, 2017
Volume
74
Issue
24
Pages
4471 - 4509
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