Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells
Abstract
Hypoxia-induced interleukin-32β (IL-32β) shifts the metabolic program to the enhanced glycolytic pathway. In the present study, the underlying mechanism by which hypoxia-induced IL-32β stability is regulated was investigated in ovarian cancer cells. IL-32β expression increased under hypoxic conditions in ovarian cancer cells as it did in breast cancer cells. The amount of IL-32β was regulated by post-translational control rather than by...
Paper Details
Title
Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells
Published Date
Jul 17, 2017
Journal
Volume
8
Issue
41
Pages
69833 - 69846
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