Sequential drain amylase to guide drain removal following pancreatectomy

BackgroundAlthough used as criterion for early drain removal, postoperative day (POD) 1 drain fluid amylase (DFA) ≤ 5000 U/L has low negative predictive value for clinically relevant postoperative pancreatic fistula (CR-POPF). It was hypothesized that POD3 DFA ≤ 350 could provide further information to guide early drain removal.MethodsData from a pancreas surgery consortium database for pancreatoduodenectomy and distal pancreatectomy patients...