Eighth annual INTERMACS report: Special focus on framing the impact of adverse events

•Greater than 22,000 patients have been entered into the INTERMACS database over the past decade.•The proportion of patients with ambulatory heart failure receiving devices has decreased slightly over the past 2 years.•Overall Kaplan-Meier survival during support is 81% at 1 year and 70% at 2 years.•INTERMACS profiles 1 and 2 as well as renal dysfunction and right heart failure continue to be important risk factors for early mortality.•Early...