SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
Abstract
Cellular glucose uptake may involve either non-concentrative glucose carriers of the GLUT family or Na+-coupled glucose-carrier SGLT1, which accumulates glucose against glucose gradients and may thus accomplish cellular glucose uptake even at dramatically decreased extracellular glucose concentrations. SGLT1 is not only expressed in epithelia but as well in tumour cells and immune cells. Immune cell functions strongly depend on their metabolism,...
Paper Details
Title
SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
Published Date
Jan 1, 2017
Volume
42
Issue
4
Pages
1358 - 1365
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