“Metformin-resistant” folic acid producing probiotics or folic acid against metformin’s adverse effects like diarrhea
Abstract
Metformin, first line medication in the treatment of type2 diabetes by millions of patients worldwide, causes gastrointestinal adverse effects (i.e. diarrhea) in approximately 30% of patients, frequently leading to discontinuation. Interestingly, metformin was reported to increase life span in a microscopic worm, Caenorhabditis elegans, by decreasing folate and methionine production of bacteria that this worm uses as a food source. Metformin can...
Paper Details
Title
“Metformin-resistant” folic acid producing probiotics or folic acid against metformin’s adverse effects like diarrhea
Published Date
Sep 1, 2017
Journal
Volume
106
Pages
33 - 34
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