Self-identification of nonpharmaceutical fentanyl exposure following heroin overdose

Published on Jan 2, 2018in Clinical Toxicology4.398
· DOI :10.1080/15563650.2017.1339889
Matthew K. Griswold3
Estimated H-index: 3
(UMMS: University of Massachusetts Medical School),
Peter R. Chai11
Estimated H-index: 11
(Brigham and Women's Hospital)
+ 5 AuthorsKavita M. Babu19
Estimated H-index: 19
(UMMS: University of Massachusetts Medical School)
AbstractObjective: To compare user self-identification of nonpharmaceutical fentanyl exposure with confirmatory urine drug testing in emergency department (ED) patients presenting after heroin overdose.Methods: This was a cross-sectional study of adult ED patients who presented after a heroin overdose requiring naloxone administration. Participants provided verbal consent after which they were asked a series of questions regarding their knowledge, attitudes and beliefs toward heroin and nonpharmaceutical fentanyl. Participants also provided urine samples, which were analyzed using liquid chromatography coupled to quadrupole time-of-flight mass spectrometry to identify the presence of fentanyl, heroin metabolites, other clandestine opioids, common pharmaceuticals and drugs of abuse.Results: Thirty participants were enrolled in the study period. Ten participants (33%) had never required naloxone for an overdose in the past, 20 participants (67%) reported recent abstinence, and 12 participants (40%) reported...
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