Effect of High Dose Acetaminophen on Liver Function Tests in Healthy Subjects

Acetaminophen (APAP) is widely used for pain relief, and it is known to cause liver injury in the case of overdose. However, several cases are often found who show slight and self-limiting increase in liver function tests (LFT) including AST and ALT without evident liver injury. Current study was performed to clarify the prevalence and characteristics of these cases. Apparently healthy subjects (161 male and 81 female subjects) were administered...