Hepatic perivascular mesenchymal stem cells with myogenic properties

Pericytes are multipotent mesenchymal stem cells located on the walls of blood vessels in various organs and are characterized as CD146+ cells. In this study, we first immunohistochemically detected pericytes in the perivascular regions of liver from two mouse genotypes, namely wild-type (WT) and myostatin null (Mstn−/−). We further isolated pericytes using sorting as CD146+ CD34− CD56− CD45− cells. The main finding of this study involves the...