Polymorphisms in VEGFA gene affect the antihypertensive responses to enalapril

Volume: 71, Issue: 8, Pages: 949 - 957
Published: May 24, 2015
Abstract
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that affects blood pressure by promoting vasodilation mediated by nitric oxide. Angiotensin-converting enzyme inhibitors (ACEi) up-regulate the VEGF expression; thus, genetic polymorphisms in the VEGFA gene could affect the antihypertensive responses to these drugs. Hypertensive patients (n = 102) were prospectively treated only with the ACEi enalapril for 60 days. We...
Paper Details
Title
Polymorphisms in VEGFA gene affect the antihypertensive responses to enalapril
Published Date
May 24, 2015
Volume
71
Issue
8
Pages
949 - 957
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