Nuclear-Encoded Mitochondrial mRNAs: A Powerful Force in Axonal Growth and Development
Abstract
Axons, their growth cones, and synaptic nerve terminals are neuronal subcompartments that have high energetic needs. As such, they are enriched in mitochondria, which supply the ATP necessary to meet these demands. To date, a heterogeneous population of nuclear-encoded mitochondrial mRNAs has been identified in distal axons and growth cones. Accumulating evidence suggests that the local translation of these mRNAs is required for mitochondrial...
Paper Details
Title
Nuclear-Encoded Mitochondrial mRNAs: A Powerful Force in Axonal Growth and Development
Published Date
Jun 14, 2017
Journal
Volume
24
Issue
2
Pages
142 - 155
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