Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes
Abstract
Exocytic carriers convey neo-synthesized components from the Golgi apparatus to the cell surface. While the release and anterograde movement of Golgi-derived vesicles require the small GTPase RAB6, its effector ELKS promotes the targeting and docking of secretory vesicles to particular areas of the plasma membrane. Here, we show that specialized cell types exploit and divert the secretory pathway towards lysosome related organelles. In cultured...
Paper Details
Title
Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes
Published Date
Jun 13, 2017
Journal
Volume
8
Issue
1
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