Unexpected consequences: exon skipping caused by CRISPR-generated mutations
Abstract
A new study finds that splicing disruption is a frequent consequence of mutations generated by CRISPR/Cas9 gene-editing technology, and alleles designed to be null can express aberrant proteins. This new information allows enhanced quality control procedures to select the best mutant alleles generated by CRISPR/Cas9. Please see related Method article:...
Paper Details
Title
Unexpected consequences: exon skipping caused by CRISPR-generated mutations
Published Date
Jun 14, 2017
Journal
Volume
18
Issue
1
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