Regulating STING in health and disease
Abstract
The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INterferon Genes (STING)”. STING has been found to mediate type I interferon response downstream of cyclic dinucleotides and a number of DNA and RNA inducing signalling pathway. In addition to its physiological function, a rapidly increasing...
Paper Details
Title
Regulating STING in health and disease
Published Date
Jun 7, 2017
Journal
Volume
14
Issue
1
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Notes
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