Diverse stimuli engage different neutrophil extracellular trap pathways
Abstract
Neutrophils release neutrophil extracellular traps (NETs) which ensnare pathogens and have pathogenic functions in diverse diseases. We examined the NETosis pathways induced by five stimuli; PMA, the calcium ionophore A23187, nigericin, Candida albicans and Group B Streptococcus. We studied NET production in neutrophils from healthy donors with inhibitors of molecules crucial to PMA-induced NETs including protein kinase C, calcium, reactive...
Paper Details
Title
Diverse stimuli engage different neutrophil extracellular trap pathways
Published Date
Jun 2, 2017
Journal
Volume
6
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