Intensity-Independent Noise Filtering in FT MS and FT MS/MS Spectra for Shotgun Lipidomics
Abstract
Shotgun lipidomics relies on the direct infusion of total lipid extracts into a high resolution tandem mass spectrometer. A single shotgun analysis produces several hundred of densely populated FT MS and FT MS/MS spectra, each of which might comprise thousands of peaks although a very small percentage of those belong to lipids. Eliminating noise by adjusting a minimal peak intensity threshold is biased and inefficient since lipid species and...
Paper Details
Title
Intensity-Independent Noise Filtering in FT MS and FT MS/MS Spectra for Shotgun Lipidomics
Published Date
Jun 15, 2017
Journal
Volume
89
Issue
13
Pages
7046 - 7052
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