Bacterial Siderophores Hijack Neutrophil Functions
Abstract
Neutrophils are the primary immune cells that respond to inflammation and combat microbial transgression. To thrive, the bacteria residing in their mammalian host have to withstand the antibactericidal responses of neutrophils. We report that enterobactin (Ent), a catecholate siderophore expressed by Escherichia coli, inhibited PMA-induced generation of reactive oxygen species (ROS) and neutrophil extracellular traps (NETs) in mouse and human...
Paper Details
Title
Bacterial Siderophores Hijack Neutrophil Functions
Published Date
Jun 1, 2017
Journal
Volume
198
Issue
11
Pages
4293 - 4303
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