BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
Abstract
In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test. Our aim in this study was to investigate the diagnostic value of BRCA1/2 methylation in distinguishing breast carcinomas of BRCA1 and BRCA2 germline mutation carriers from sporadic breast carcinomas using a recently developed BRCA methylation assay based on...
Paper Details
Title
BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
Published Date
May 31, 2017
Journal
Volume
19
Issue
1
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