Propagation of Tau aggregates
Abstract
Since 2009, evidence has accumulated to suggest that Tau aggregates form first in a small number of brain cells, from where they propagate to other regions, resulting in neurodegeneration and disease. Propagation of Tau aggregates is often called prion-like, which refers to the capacity of an assembled protein to induce the same abnormal conformation in a protein of the same kind, initiating a self-amplifying cascade. In addition, prion-like...
Paper Details
Title
Propagation of Tau aggregates
Published Date
May 30, 2017
Journal
Volume
10
Issue
1
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Notes
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