Structures of minor glucosides from the Far Eastern high-mountain endemic plant Ligularia alticola Worosch. Screening of bioactivity for some glycosides from L. alticola

Two new minor eremophilane-type sesquiterpene glucosides, alticolosides H (1) and I (2) along with known earlier lignan glucosides (−)-pinoresinol-4′-O-β-d-glucoside, plucheoside D1 and tortoside F were isolated from aerial parts of the endemic Far Eastern species Ligularia alticola Worosch. (Family Asteraceae). Structures of the glycosides were elucidated by 2D NMR spectroscopy and HRESIMS. The absolute stereochemistry of 1 and 2 was determined...