Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease
Abstract
Plasminogen activator inhibitor type 1 (PAI-1) plays an essential role in the fibrinolysis system and thrombosis. Population studies have reported that blood PAI-1 levels are associated with increased risk of coronary heart disease (CHD). However, it is unclear whether the association reflects a causal influence of PAI-1 on CHD risk.To evaluate the association between PAI-1 and CHD, we applied a 3-step strategy. First, we investigated the...
Paper Details
Title
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease
Published Date
Nov 6, 2017
Volume
6
Issue
6
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