Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis
Abstract
Clinical trials of stem cell therapy to treat ischemic heart disease primarily use heterogeneous stem cell populations. Small benefits occur via paracrine mechanisms that include stimulating angiogenesis, and increased understanding of these mechanisms would help to improve patient outcomes. Cardiosphere-derived-cells (CDCs) are an example of these heterogeneous stem cell populations, cultured from cardiac tissue. CDCs express endoglin, a...
Paper Details
Title
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis
Published Date
May 1, 2017
Journal
Volume
8
Issue
5
Pages
1287 - 1298
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