Basic science and pathogenesis of ageing with HIV
Abstract
: The increased prevalence of age-related comorbidities and mortality is worrisome in ageing HIV-infected patients. Here, we aim to analyse the different ageing mechanisms with regard to HIV infection. Ageing results from the time-dependent accumulation of random cellular damage. Epigenetic modifications and mitochondrial DNA haplogroups modulate ageing. In antiretroviral treatment-controlled patients, epigenetic clock appears to be advanced,...
Paper Details
Title
Basic science and pathogenesis of ageing with HIV
Published Date
Jun 1, 2017
Journal
Volume
31
Issue
Supplement 2
Pages
S105 - S119
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Notes
History