Original paper
Recipient-Derived BAFF and Alloantigen Synergistically Activate B Cells in Murine Chronic Gvhd
Abstract
Increased B cell-activating factor (BAFF) and aberrant B cell survival and activation are associated with chronic graft versus host disease (cGVHD) in patients. Whether excessive BAFF production has a pathologic role in the development of cGVHD after allogeneic hematopoietic stem cell transplantation (allo-HCT) remains unknown. Herein, we address this hypothesis by employing BAFF knockout (KO) and BAFF overexpressing (Tg) donor mice in the major...
Paper Details
Title
Recipient-Derived BAFF and Alloantigen Synergistically Activate B Cells in Murine Chronic Gvhd
Published Date
Dec 2, 2016
Journal
Volume
128
Issue
22
Pages
498 - 498
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Notes
History