Analysis of DNA-damage response to ionizing radiation in serum-shock synchronized human fibroblasts
Abstract
Many aspects of cellular physiology, including cellular response to genotoxic stress, are related to the circadian rhythmicity induced by the molecular clock. The current study investigated if the cellular response to DNA damage is in relation to endogenous expression levels of the PER2 protein, a key component of the molecular regulatory system that confers rhythmicity in mammalian cells. Human normal fibroblasts (CCD-34Lu) were subjected to...
Paper Details
Title
Analysis of DNA-damage response to ionizing radiation in serum-shock synchronized human fibroblasts
Published Date
May 3, 2017
Journal
Volume
33
Issue
4
Pages
373 - 388
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