Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast‐enhanced μCT

Articular cartilage lines the load‐bearing surfaces of long bones and undergoes compositional and structural degeneration during osteoarthritis progression. Contrast enhanced microcomputed tomography (μCT) is being applied to a variety of preclinical models, including the mouse, to map structural and compositional properties in 3‐D. The thinness (∼30–50 μm) and high cellularity of mouse articular cartilage presents a significant imaging...