922. Reward Anticipation in Early Expression of Psychotic Disorder: A Functional MRI Approach

Previous research in patients with psychotic disorder has shown reduced activation in the brain’s reward system (ventral medial prefrontal cortex (VMPFC), ventral striatum (VS), nucleus accumbens, caudate, putamen, ventral tegmental area (VTA)). The literature on the reward system in subclinical psychosis is limited and inconclusive, describing both hypo- and hyper-activation. Therefore, reward anticipation in individuals with subclinical...