Altered Expression of Hippo Signaling Pathway Molecules in Intrahepatic Cholangiocarcinoma

<b><i>Objective:</i></b> MOB1, a core component of the Hippo signaling pathway, suppresses cell proliferation, and MOB1 liver conditional knockout mice develop intrahepatic cholangiocarcinoma (ICC). However, its clinical significance in human ICC has not been established. The aim of this study was to characterize protein levels and the role of Hippo and TGF pathways in ICCs. <b><i>Methods:</i></b>...