Brief report The antifibrinolytic function of factor XIII is exclusively expressed through 2-antiplasmin cross-linking
Published: Jan 1, 2017
Abstract
Factor XIII (FXIII) generates fibrin-fibrin and fibrin-inhibitor cross-links. Our flow model, which is sensitive to cross-linking, was used to assess the effects of FXIII and the fibrinolytic inhibitor, 2antiplasmin (2AP) onfibrinolysis. Plasma model thrombi formed from FXIII or 2AP depleted plasma lysed at strikingly similar rates, 9-fold faster than pooled normal plasma (PNP). In contrast, no change was observed on depletion of PAI-1 or...
Paper Details
Title
Brief report The antifibrinolytic function of factor XIII is exclusively expressed through 2-antiplasmin cross-linking
Published Date
Jan 1, 2017
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