Marker-free coselection for CRISPR-driven genome editing in human cells

Published on Jun 1, 2017in Nature Methods28.467
· DOI :10.1038/nmeth.4265
D. Agudelo15
Estimated H-index: 15
Alexis Duringer1
Estimated H-index: 1
+ 9 AuthorsYannick Doyon24
Estimated H-index: 24
A gain-of-function mutation in a sodium/potassium pump renders cells resistant to a small-molecule drug and provides an efficient coselection strategy to enrich for CRISPR-induced mutations at an independent locus.
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