High-avidity IgA protects the intestine by enchaining growing bacteria
Abstract
Vaccine-induced high-avidity IgA can protect against bacterial enteropathogens by directly neutralizing virulence factors or by poorly defined mechanisms that physically impede bacterial interactions with the gut tissues ('immune exclusion'). IgA-mediated cross-linking clumps bacteria in the gut lumen and is critical for protection against infection by non-typhoidal Salmonella enterica subspecies enterica serovar Typhimurium (S. Typhimurium)....
Paper Details
Title
High-avidity IgA protects the intestine by enchaining growing bacteria
Published Date
Apr 1, 2017
Journal
Volume
544
Issue
7651
Pages
498 - 502
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