Detection of prostate cancer‐specific transcripts in extracellular vesicles isolated from post‐DRE urine

Background : The measurement of gene expression in post‐digital rectal examination (DRE) urine specimens provides a non‐invasive method to determine a patient's risk of prostate cancer. Many currently available assays use whole urine or cell pellets for the analysis of prostate cancer‐associated genes, although the use of extracellular vesicles (EVs) has also recently been of interest. We investigated the expression of prostate‐, kidney‐, and...